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Interleukin 17a Antikörper

IL17A Reaktivität: Human BCA Wirt: Maus Monoclonal BL168 unconjugated
Produktnummer ABIN2665116
  • Target Alle Interleukin 17a (IL17A) Antikörper anzeigen
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    Reaktivität
    • 102
    • 54
    • 19
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    Human
    Wirt
    • 62
    • 51
    • 29
    • 8
    • 3
    Maus
    Klonalität
    • 80
    • 72
    • 1
    Monoklonal
    Konjugat
    • 68
    • 24
    • 15
    • 11
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Interleukin 17a Antikörper ist unkonjugiert
    Applikation
    • 74
    • 64
    • 49
    • 15
    • 12
    • 12
    • 12
    • 11
    • 10
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Biochemical Assay (BCA)
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    BL168
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product IL17A Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    Andere Bezeichnung
    IL-17A (IL17A Produkte)
    Synonyme
    CTLA8 antikoerper, IL-17 antikoerper, IL-17A antikoerper, IL17 antikoerper, Ctla-8 antikoerper, Ctla8 antikoerper, Il17 antikoerper, ChIL-17 antikoerper, IL-17F antikoerper, IL17A antikoerper, CTLA-8 antikoerper, interleukin 17A antikoerper, IL17A antikoerper, Il17a antikoerper
    Hintergrund
    IL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts, the enhancement of surface expression of ICAM-1 in fibroblasts, activation of NF-κB and costimulation of T cell proliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells) mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63 % , 63 %, and 72 % amino acid sequence identity to rat IL-17A, mouse IL-17A, and a protein encoded by the ORF13 gene of herpesvirus Saimiri (HVS), respectively.
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