IL16 Antikörper (AA 615-630)

Produktnummer ABIN2665114

Der Maus Monoklonal Anti-IL16-Antikörper wurde für FACS validiert. Er ist geeignet, IL16 in Proben von Human zu detektieren.

Kurzübersicht für IL16 Antikörper (AA 615-630) (ABIN2665114)

Target: IL16 (Interleukin 16 (IL16))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL16 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 14-1

Produktdetails anti-IL16 Antikörper

Bindungsspezifität: AA 615-630

Kreuzreaktivität: Maus

Aufreinigung: The antibody was purified by affinity chromatography.

Immunogen: AA 615-630 (RRKSLQSKETTAAGDS) of IL-16

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu IL16

Target: IL16 (Interleukin 16 (IL16))

Andere Bezeichnung: IL-16

Hintergrund: Interleukin-16 is a proinflammatory cytokine synthesized as a 68 kD precursor molecule (pro-IL-16). After cleavage of pro-IL-16 by caspase-3, IL-16 is released as a 12 kD protein, but its biologic activities are exerted by a tetramer. IL-16 is a chemoattractant for CD4+ T cells, monocytes, and eosinophils. On T cells, IL-16 upregulates CD25 and class II expression, and also inhibits HIV-1 replication in vitro by repressing the transcription of the HIV-1 long terminal repeat. IL-16 is expressed by lymphocytes, macrophages, eosinophils, mast cells, epithelial cells, and fibroblasts. CD4 and CD9 are the receptors of IL-16.