FPR3 Antikörper

Produktnummer ABIN2664985

Der Maus Monoklonal Anti-FPR3-Antikörper wurde für ELISA, IHC, IF, FACS, ICC, CyTOF und ICFC validiert. Er ist geeignet, FPR3 in Proben von Human zu detektieren.

Kurzübersicht für FPR3 Antikörper (ABIN2664985)

Target: FPR3 (Formyl Peptide Receptor 3 (FPR3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FPR3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Cytometry by Time of Flight (CyTOF), Intracellular Flow Cytometry (ICFC)

Klon: K102B9

Produktdetails anti-FPR3 Antikörper

Aufreinigung: The antibody was purified by affinity chromatography.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu FPR3

Target: FPR3 (Formyl Peptide Receptor 3 (FPR3))

Andere Bezeichnung: FPR3

Hintergrund: FPR3, also known as FPRL2, belongs to the formyl peptide receptor family which includes FPR1, FPR2, and FPR3. Monocytes express FPR1, 2, and 3, upon differentiation into macrophages, expression of these receptors is maintained. Two ligands, humanin and F2L have been identified. Humanin is expressed in the heart, skeletal muscle, kidney, and liver but is not expressed in the immune system. F2L is a heme-binding protein first identified in the spleen. Binding of FPRL2 and F2L induces Ca2+ mobilization and neutrophil chemotaxis. Low level of expression of FPRL2 has also been reported on NK cells.