Fc epsilon RI/FCER1A Antikörper
Kurzübersicht für Fc epsilon RI/FCER1A Antikörper (ABIN2664964)
Target
Alle Fc epsilon RI/FCER1A (FCER1A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- The antibody was purified by affinity chromatography.
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Isotyp
- IgG
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anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 42-103) antibody
FCER1A Reaktivität: Human, Maus FACS, WB, ELISA Wirt: Maus Monoclonal 1F2A9 unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 1-257) antibodyFCER1A Reaktivität: Human WB, ELISA, RNAi Wirt: Maus Monoclonal 2C12-3B6 unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 26-205) antibodyFCER1A Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) antibodyFCER1A Reaktivität: Human FACS, WB, ELISA, IP, IF Wirt: Maus Monoclonal 9E1 unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 1-257) antibodyFCER1A Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (C-Term) antibodyFCER1A Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 24-204) antibodyFCER1A Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) antibody (APC)FCER1A Reaktivität: Maus FACS Wirt: Armenischer Hamster Monoclonal MAR-1 APC
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 101-220) antibodyFCER1A Reaktivität: Human WB, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 1-257) antibodyFCER1A Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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Andere Bezeichnung
- Fc epsilon RI alpha
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Hintergrund
- FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via Fcε RIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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