DDX5 Antikörper
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- Target Alle DDX5 Antikörper anzeigen
- DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))
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Reaktivität
- Human, Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser DDX5 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Aufreinigung
- The antibody was purified by affinity chromatography.
- Klon
- 14B9A58
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product DDX5 Primärantikörper
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anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) (AA 475-614) antibody
DDX5 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 4F1C12 unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) (AA 1-614) antibodyDDX5 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) (AA 1-614) antibodyDDX5 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) (C-Term) antibodyVerified DDX5 Reaktivität: Human, Maus WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) (AA 1-290) antibodyDDX5 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) antibodyDDX5 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Monoclonal 2C3 unconjugated Recombinant Antibody
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) (C-Term) antibodyDDX5 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) (C-Term) antibodyDDX5 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) (C-Term) antibodyDDX5 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) (AA 1-210) antibodyDDX5 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))
- Andere Bezeichnung
- DDX5 (DDX5 Produkte)
- Hintergrund
- DDX5, also named RNA helicase p68, is a prototypic member of the DEAD (Asp-Glu-Ala-Asp) box family. DDX5 has been shown to be involved in the processes requiring the alteration of RNA structures, such as the maturation of pre-mRNA, rRNA, and miRNA. DDX5 also plays important helicase-independent roles in transcriptional regulation. DDX5 can act as a transcriptional coactivator of the androgen receptor (AR), estrogen receptor α (ERα), tumor suppressor p53, MyoD, RUNX2, and β -catenin, which are involved in the regulation of cell proliferation, differentiation, and tumorigenesis. DDX5 has been shown to be up-regulated in various cancers, including breast cancer, prostate cancer, and colorectal cancer, suggesting that DDX5 may participate in tumor development. DDX5 can also act as a transcriptional repressor through interacting with HDAC1.
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus
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