CXCL16 Antikörper
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- Target Alle CXCL16 Antikörper anzeigen
- CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CXCL16 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
- Aufreinigung
- The antibody was purified by affinity chromatography.
- Klon
- 22-19-12
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CXCL16 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))
- Andere Bezeichnung
- CXCL16 (CXCL16 Produkte)
- Hintergrund
- CXCL16, a 27 kD chemokine, exists in membrane-bound and soluble forms. Unlike classic chemokines, CXCL16 possesses a mucin-like stalk, a transmembrane domain, and a cytoplasmic tail with a tyrosine phosphorylation domain, allowing it to be expressed on the cell surface. Structurally, it is similar to fractalkine. It is expressed by dendritic cells, monocytes, and T cells. T cells can also migrate in response to CXCL16. CXCL16 can also act as a scavenger receptor on macrophages. Its receptor is CXCR6/Bonzo. It can bind oxidized LDL and thus may play an important role in atherosclerosis. Recent studies have shown a role for CXCL16 in kidney fibrosis and in autoimmunity. CXCL16 is also a co-receptor for HIV.
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