CD8 alpha Antikörper
Kurzübersicht für CD8 alpha Antikörper (ABIN2664863)
Target
Alle CD8 alpha (CD8A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- The antibody was purified by affinity chromatography.
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Isotyp
- IgG2a kappa
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anti-CD8a Molecule (CD8A) (AA 22-235) antibody
CD8A Reaktivität: Human FACS, WB, ELISA Wirt: Maus Monoclonal 8H8A8 unconjugated
anti-CD8a Molecule (CD8A) antibodyCD8A Reaktivität: Maus FACS, IP, IHC (fro), IHC (p), ICC, Func Wirt: Ratte Monoclonal 53-6-7 unconjugated
anti-CD8a Molecule (CD8A) antibodyCD8A Reaktivität: Maus FACS, IP, IHC (fro), IHC (p), ICC Wirt: Ratte Monoclonal 53-6-7 unconjugated
anti-CD8a Molecule (CD8A) (AA 51-150) antibodyCD8A Reaktivität: Human, Ratte, Huhn FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-CD8a Molecule (CD8A) antibodyCD8A Reaktivität: Human IHC, WB, IP, ELISA Wirt: Kaninchen Monoclonal 2F2 unconjugated Recombinant Antibody
anti-CD8a Molecule (CD8A) (AA 22-182) antibodyCD8A Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 6A9A5 unconjugated
anti-CD8a Molecule (CD8A) antibodyCD8A Reaktivität: Human IHC, StM, ISt Wirt: Maus Monoclonal C8-468 unconjugated
anti-CD8a Molecule (CD8A) (AA 28-196) antibodyCD8A Reaktivität: Maus, Ratte FACS, IHC, WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-CD8a Molecule (CD8A) (AA 150-180) antibodyCD8A Reaktivität: Human FACS, IHC, WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-CD8a Molecule (CD8A) (AA 59-88) antibodyCD8A Reaktivität: Human IHC, WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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Andere Bezeichnung
- CD8a
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Hintergrund
- CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
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Pathways
- T-Zell Rezeptor Signalweg
Target
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