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- Target Alle CD77 Produkte
- CD77
- Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD77 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Aufreinigung
- The antibody was purified by affinity chromatography.
- Klon
- 5B5
- Isotyp
- IgM kappa
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anti-CD77 antibody
Reaktivität: Human FACS, ICC, IHC (fro) Wirt: Ratte Monoclonal 38-13 unconjugated
anti-CD77 antibody (FITC)Reaktivität: Human FACS Wirt: Ratte Monoclonal 38-13 FITC
anti-CD77 antibody (PE)Reaktivität: Human FACS Wirt: Ratte Monoclonal 38-13 PE
anti-CD77 antibody (FITC)Reaktivität: Human FACS, IHC, IP Wirt: Maus Monoclonal 5B5 FITC
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- CD77
- Abstract
- CD77 Produkte
- Hintergrund
- CD77, also known as Gb3S, A14GALT, A4GALT1, is a type II membrane protein. It was found specifically expressed on Burkitt's lymphoma cells and on a subset of germinal center B lymphocytes. CD77 has been described as a receptor for Shiga Toxin and Verotoxin 1 (VT1), which is produced by Shigella dysenteriae and some strains of E. coli . It is used as a marker for germinal center stage B-cells. CD19 has been reported as a ligand for D77 and their interaction functions in adhesion and signal transduction at a specific stage of B cell development. Studies have shown that cross-linking CD77 induces apoptosis in some B cell lines.
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