Neuropilin 1 Antikörper

Produktnummer ABIN2664540

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Neuropilin 1 in ELISA (Capture) und ELISPOT (Capture). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Neuropilin 1 Antikörper (ABIN2664540)

Target: Neuropilin 1 (NRP1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Neuropilin 1 Antikörper ist unkonjugiert

Applikation: ELISA (Capture), ELISpot (Capture) (ELISPOT (Capture))

Klon: 12C2

Produktdetails anti-Neuropilin 1 Antikörper

Aufreinigung: The antibody was purified by affinity chromatography.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu Neuropilin 1

Target: Neuropilin 1 (NRP1)

Andere Bezeichnung: CD304

Hintergrund: CD304, also known as neuropilin-1, BDCA-4 and VEGF165R, is a 140 kD type I transmembrane protein. Its extracellular region contains two CUB, two FV/FVIII, and one MAM domain, a soluble isoform is produced by alternative mRNA splicing. CD304 is involved in angiogenesis, neural development, and tumor metastasis. It is expressed by plasmacytoid dendritic cells, thymocytes, neurons, endothelium, and a subset of TFH cells. CD304 is also expressed in several carcinomas, and a high expression of this molecule in prostate cancer correlates with a poor prognosis.

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals