CXCR4 Antikörper
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- Target Alle CXCR4 Antikörper anzeigen
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CXCR4 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Kreuzreaktivität
- Schimpanse, Pavian, Cynomolgus, Rhesusaffen, Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Sooty mangabey (Cercocebus atys), Green Monkey (Chlorocebus sabaeus)
- Aufreinigung
- The antibody was purified by affinity chromatography.
- Klon
- 12G5
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product CXCR4 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- Andere Bezeichnung
- CD184 (CXCR4 Produkte)
- Hintergrund
- CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.
- Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
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