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CXCR4 Antikörper

Der Maus Monoklonal Anti-CXCR4-Antikörper wurde für BCA validiert. Er ist geeignet, CXCR4 in Proben von Human zu detektieren.
Produktnummer ABIN2664313

Kurzübersicht für CXCR4 Antikörper (ABIN2664313)

Target

Alle CXCR4 Antikörper anzeigen
CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reaktivität

  • 163
  • 91
  • 66
  • 21
  • 11
  • 10
  • 10
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 134
  • 35
  • 12
  • 9
  • 2
  • 1
  • 1
  • 1
Maus

Klonalität

  • 141
  • 52
  • 1
Monoklonal

Konjugat

  • 117
  • 9
  • 8
  • 7
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CXCR4 Antikörper ist unkonjugiert

Applikation

  • 129
  • 66
  • 56
  • 53
  • 35
  • 30
  • 26
  • 26
  • 25
  • 25
  • 9
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Biochemical Assay (BCA)

Klon

12G5
  • Kreuzreaktivität

    Schimpanse, Pavian, Cynomolgus, Rhesusaffen, Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Sooty mangabey (Cercocebus atys), Green Monkey (Chlorocebus sabaeus)

    Aufreinigung

    The antibody was purified by affinity chromatography.

    Isotyp

    IgG2a kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

    Andere Bezeichnung

    CD184

    Hintergrund

    CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.

    Pathways

    Regulation of Cell Size, CXCR4-mediated Signaling Events
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