Der Maus Monoklonal anti-VPREB1 Antikörper (Klon HSL96) (ABIN2664299) detektiert spezifisch VPREB1 in FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Target
VPREB1
(Pre-B Lymphocyte 1 (VPREB1))
Andere Bezeichnung
CD179a
Hintergrund
CD179a is an 18 kD Ig V-like protein expressed on pro-B and early pre-B cells. It is a member of the Ig gene superfamily, known as VpreB, VPREB1, and IGVPB. CD179a noncovalently associates with CD179b (λ5) to form a surrogate light (SL) chain. The SL chain is complexed with membrane bound IgM heavy (μH) chain and CD79a/CD79b heterodimer to form the pre-B-cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation though it has been reported that the pre-BCR complex plays a critical role in B cell development.