CCRL2 Antikörper

Produktnummer ABIN2664102

Dieser Maus Monoklonal Antikörper detektiert spezifisch CCRL2 in IHC und ELISA (Capture). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CCRL2 Antikörper (ABIN2664102)

Target: CCRL2 (Chemokine (C-C Motif) Receptor-Like 2 (CCRL2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCRL2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA (Capture)

Klon: K097F7

Produktdetails anti-CCRL2 Antikörper

Aufreinigung: The antibody was purified by affinity chromatography.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CCRL2

Target: CCRL2 (Chemokine (C-C Motif) Receptor-Like 2 (CCRL2))

Andere Bezeichnung: CCRL2

Hintergrund: CCRL2 (C-C chemokine receptor-like 2) is a seven transmembrane, G-protein coupled receptor with two isoforms generated from alternative splicing. CCRL2 is expressed by the majority of cell types of hematopoietic origin, including monocytes, macrophages, neutrophils, lymphocytes, and NK cells. In some cell types, its expression is upregulated by inflammatory stimuli. CCRL2 is important for the development of Th2 responses and may act as a decoy receptor capturing and endocyting its ligands CCL5 and CCL19, however, it has been found that CCRL2 captures and retains chemerin/RARRES2 on its cell surface, presenting it to neighboring cells.