BIN1 Antikörper

Produktnummer ABIN2664071

Dieser Anti-BIN1 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von BIN1 in FACS. Geeignet für Human.

Kurzübersicht für BIN1 Antikörper (ABIN2664071)

Target: BIN1 (Bridging Integrator 1 (BIN1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BIN1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 99D

Produktdetails anti-BIN1 Antikörper

Aufreinigung: The antibody was purified by affinity chromatography.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu BIN1

Target: BIN1 (Bridging Integrator 1 (BIN1))

Andere Bezeichnung: Bin1

Hintergrund: Bridging integrator 1 (Bin1) is a conserved member of the BAR family of genes that have been implicated in diverse cellular processes including endocytosis, cell polarity, programmed cell death, and stress signaling. It is involved in membrane remodeling and is one of the important genes in predicting risk for Alzheimer's disease (AD). Alternative splicing of the gene results in ten transcript variants. Isoforms 1-7 are expressed predominantly in the central nervous system. Isoform 8 is expressed specifically in muscle, and defects in BIN1 cause autosomal recessive myotubular myopathy. Isoforms 9 and 10 are ubiquitously expressed and may act as tumor repressors.