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Integrin beta 7 Antikörper (PE)

Dieses Anti-Integrin beta 7-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von Integrin beta 7 in FACS. Geeignet für Human und Maus.
Produktnummer ABIN2663810

Kurzübersicht für Integrin beta 7 Antikörper (PE) (ABIN2663810)

Target

Alle Integrin beta 7 (ITGB7) Antikörper anzeigen
Integrin beta 7 (ITGB7)

Reaktivität

  • 77
  • 30
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 51
  • 19
  • 7
  • 4
  • 1
Ratte

Klonalität

  • 52
  • 28
  • 2
Monoklonal

Konjugat

  • 37
  • 8
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Integrin beta 7 Antikörper ist konjugiert mit PE

Applikation

  • 41
  • 27
  • 22
  • 13
  • 13
  • 9
  • 8
  • 8
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

FIB504
  • Kreuzreaktivität

    Schimpanse, Pavian, Cynomolgus, Rhesusaffen

    Aufreinigung

    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    Isotyp

    IgG2a kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Protect from prolonged exposure to light. Do not freeze.

    Lagerung

    4 °C

    Informationen zur Lagerung

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    Integrin beta 7 (ITGB7)

    Andere Bezeichnung

    Integrin Beta7

    Hintergrund

    Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.

    Pathways

    Integrin Complex
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