VPREB1 Antikörper (PE)

Produktnummer ABIN2663102

Produktdetails anti-VPREB1 Antikörper (PE)

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VPREB1 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Klon: HSL96

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu VPREB1

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Andere Bezeichnung: CD179a (VPREB1 Produkte)

Synonyme: IGI antikoerper, IGVPB antikoerper, VPREB antikoerper, VpreB antikoerper, CD179a antikoerper, Vpreb-1 antikoerper, V-set pre-B cell surrogate light chain 1 antikoerper, immunoglobulin iota chain antikoerper, immunoglobulin iota chain-like antikoerper, pre-B lymphocyte 1 antikoerper, pre-B lymphocyte gene 1 antikoerper, VPREB1 antikoerper, LOC698810 antikoerper, LOC486411 antikoerper, Vpreb1 antikoerper

Hintergrund: CD179a is an 18 kD Ig V-like protein expressed on pro-B and early pre-B cells. It is a member of the Ig gene superfamily, known as VpreB, VPREB1, and IGVPB. CD179a noncovalently associates with CD179b (λ5) to form a surrogate light (SL) chain. The SL chain is complexed with membrane bound IgM heavy (μH) chain and CD79a/CD79b heterodimer to form the pre-B-cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation though it has been reported that the pre-BCR complex plays a critical role in B cell development.

Pathways: Production of Molecular Mediator of Immune Response, Regulation of Cell Size