GPR77 Antikörper (PE)

Produktnummer ABIN2662916

Der PE-konjugierte Maus Monoklonal anti-GPR77 Antikörper (Klon 1D9-M12) (ABIN2662916) detektiert spezifisch GPR77 in IHC, FACS und BR. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für GPR77 Antikörper (PE) (ABIN2662916)

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GPR77 Antikörper ist konjugiert mit PE

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS), Blocking Reagent (BR)

Klon: 1D9-M12

Produktdetails anti-GPR77 Antikörper (PE)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu GPR77

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Andere Bezeichnung: C5L2

Hintergrund: C5L2 (C5a receptor-like 2) is a seven-transmembrane orphan receptor, also known as GPR77, which shares significant homology to C5a receptor (CD88). But it is a decoy receptor without G-protein coupling. C5L2 is co-expressed with C5aR on many kinds of cells, such as neutrophils, immature dendritic cells, mast cells, macrophages, and astrocytes. C5L2 binds C5a with similar high affinity as C5aR and relatively higher affinity for C5a-des-Arg than with C5aR. Clone 1D9-M12 is known to block C5a binding to C5L2, but does not react with C5a receptor.