TCR V Beta8.1 Antikörper (PE)

Produktnummer ABIN2662873

Der Maus Monoklonal Anti--Antikörper wurde für ELISA (Detection) validiert. Er ist geeignet, in Proben von Maus zu detektieren.

Kurzübersicht für TCR V Beta8.1 Antikörper (PE) (ABIN2662873)

Target: TCR V Beta8.1

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: PE

Applikation: ELISA (Detection)

Klon: MR5-2

Produktdetails

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Antigendetails

Target: TCR V Beta8.1

Hintergrund: Vβ8 T cell receptor (TCR Vβ8) subfamily has three members, Vβ8.1, 8.2, and 8.3. These subfamily members are variants of the TCR β chain that along with the TCR α chain forms the TCR heterodimer, responsible for the recognition of peptides presented by the MHC molecules. Murine Vβ8+ T cells recognize the superantigen staphylococcal enterotoxin B (SEB), in vivo administration of SEB results in the negative selection of Vβ8+ cells in the thymus. Vβ8 is one of the most frequently found β chains on the infiltrating T cells in the brain of mice with experimental autoimmune encephalomyelitis (EAE), and on the T cells response to Toxoplasma gondii.