TCR V beta 11 Antikörper (PE)

Produktnummer ABIN2662861

Der Ratte Monoklonal Anti--Antikörper wurde für IF, IP und WB validiert. Er ist geeignet, in Proben von Maus zu detektieren.

Kurzübersicht für TCR V beta 11 Antikörper (PE) (ABIN2662861)

Target: TCR V beta 11

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: PE

Applikation: Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)

Klon: RR3-15

Produktdetails

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Antigendetails

Target: TCR V beta 11

Andere Bezeichnung: TCR V Beta11

Hintergrund: T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation. V β 11-bearing T cells are largely absent from strains of mice that express MHC class II molecule I-E. It has been demonstrated that the expression of I-E molecule is necessary for the clonal deletion of V beta 11-bearing T cells, but not sufficient for the clonal elimination of V beta 11-bearing T cells.