Acetylated Lysine Antikörper (acetylated) (PE)

Produktnummer ABIN2662804

Der Maus Monoklonal Anti-Acetylated Lysine-Antikörper wurde für FACS validiert. Er ist geeignet, Acetylated Lysine in Proben von zu detektieren.

Kurzübersicht für Acetylated Lysine Antikörper (acetylated) (PE) (ABIN2662804)

Target: Acetylated Lysine

Reaktivität: Bitte anfragen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Acetylated Lysine Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: 15G10

Produktdetails anti-Acetylated Lysine Antikörper (PE)

Bindungsspezifität: acetylated

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu Acetylated Lysine

Target: Acetylated Lysine

Substanzklasse: Chemical

Hintergrund: Proteins are reversibly and dynamically acetylated on the ε-amino group of lysine by acetyltransferases and deacetylated by deacetylases. This post-translational modification can regulate protein function (interactions with other proteins and DNA binding). Histones and transcription factors (PCAF, p53, p300, etc) appear to be the major targets of acetyltransferases. Acetylation is usually associated with chromatin remodeling and transcriptional activation, although in some cases (telomeres) it is associated with gene silencing. The 15G10 antibody recognizes acetylated lysine residues on proteins.