IL16 Antikörper (AA 615-630) (PE)

Produktnummer ABIN2662757

Der PE-konjugierte Maus Monoklonal anti-IL16 Antikörper (Klon 14-1) (ABIN2662757) detektiert spezifisch IL16 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL16 Antikörper (AA 615-630) (PE) (ABIN2662757)

Target: IL16 (Interleukin 16 (IL16))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL16 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: 14-1

Produktdetails anti-IL16 Antikörper (PE)

Bindungsspezifität: AA 615-630

Kreuzreaktivität: Maus

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Immunogen: AA 615-630 (RRKSLQSKETTAAGDS) of IL-16

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu IL16

Target: IL16 (Interleukin 16 (IL16))

Andere Bezeichnung: IL-16

Hintergrund: Interleukin-16 is a proinflammatory cytokine synthesized as a 68 kD precursor molecule (pro-IL-16). After cleavage of pro-IL-16 by caspase-3, IL-16 is released as a 12 kD protein, but its biologic activities are exerted by a tetramer. IL-16 is a chemoattractant for CD4+ T cells, monocytes, and eosinophils. On T cells, IL-16 upregulates CD25 and class II expression, and also inhibits HIV-1 replication in vitro by repressing the transcription of the HIV-1 long terminal repeat. IL-16 is expressed by lymphocytes, macrophages, eosinophils, mast cells, epithelial cells, and fibroblasts. CD4 and CD9 are the receptors of IL-16.