CXCL16 Antikörper (PE)

Produktnummer ABIN2662702

Der Maus Monoklonal Anti-CXCL16-Antikörper wurde für FACS validiert. Er ist geeignet, CXCL16 in Proben von Human zu detektieren.

Kurzübersicht für CXCL16 Antikörper (PE) (ABIN2662702)

Target: CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CXCL16 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: 22-19-12

Produktdetails anti-CXCL16 Antikörper (PE)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CXCL16

Target: CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))

Andere Bezeichnung: CXCL16

Hintergrund: CXCL16, a 27 kD chemokine, exists in membrane-bound and soluble forms. Unlike classic chemokines, CXCL16 possesses a mucin-like stalk, a transmembrane domain, and a cytoplasmic tail with a tyrosine phosphorylation domain, allowing it to be expressed on the cell surface. Structurally, it is similar to fractalkine. It is expressed by dendritic cells, monocytes, and T cells. T cells can also migrate in response to CXCL16. CXCL16 can also act as a scavenger receptor on macrophages. Its receptor is CXCR6/Bonzo. It can bind oxidized LDL and thus may play an important role in atherosclerosis. Recent studies have shown a role for CXCL16 in kidney fibrosis and in autoimmunity. CXCL16 is also a co-receptor for HIV.