CD37 Antikörper (PE)

Produktnummer ABIN2662623

Dieser Ratte Monoklonal Antikörper erkennt spezifisch CD37 in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für CD37 Antikörper (PE) (ABIN2662623)

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD37 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: Duno85

Produktdetails anti-CD37 Antikörper (PE)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CD37

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Andere Bezeichnung: CD37

Hintergrund: CD37, also known as Tspan26 is a 40-60 kD member of the tetraspanin (TM4SF) family, with two extracellular regions and both termini in the cytoplasm. CD37 is highly expressed on mature B cells and is also expressed on T cells, monocytes, macrophages, and neutrophils, and dendritic cells to a lesser extent. CD37 forms complexes in the cell membrane with CD53, CD81, CD82, MHC class II and dectin 1. CD37 is essential for B cell survival, regulates T cell proliferation, IgA production, and is involved in dendritic cell migration. CD37 has been described as a promising target in the treatment of B cell malignancies.

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response