VPREB1 Antikörper (PE)

Produktnummer ABIN2662481

Produktdetails anti-VPREB1 Antikörper (PE)

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser VPREB1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Klon: R3

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu VPREB1

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Andere Bezeichnung: CD179a (VPREB1 Produkte)

Synonyme: IGI antikoerper, IGVPB antikoerper, VPREB antikoerper, VpreB antikoerper, CD179a antikoerper, Vpreb-1 antikoerper, V-set pre-B cell surrogate light chain 1 antikoerper, immunoglobulin iota chain antikoerper, immunoglobulin iota chain-like antikoerper, pre-B lymphocyte 1 antikoerper, pre-B lymphocyte gene 1 antikoerper, VPREB1 antikoerper, LOC698810 antikoerper, LOC486411 antikoerper, Vpreb1 antikoerper

Hintergrund: CD179a, also known as VpreB, is an 18 kD member of the Ig superfamily, with an Ig V-like domain structure (that lacks the β strand of a typical V domain). CD179a associates with CD179b to form a surrogate light (SL) chain, which associates with the IgM heavy chain and the CD79a/CD79b heterodimer to form the pre-B cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation, though it has been reported that deficiency of CD179a and/or CD179b impairs the maturation of the B cell precursors beyond the pre-B cell stage.

Pathways: Production of Molecular Mediator of Immune Response, Regulation of Cell Size