Allergin-1 Antikörper (PE)

Produktnummer ABIN2662383

Produktdetails anti-Allergin-1 Antikörper (PE)

Target: Allergin-1 (MILR1) (Mast Cell Immunoglobulin-Like Receptor 1 (MILR1))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Allergin-1 Antikörper ist konjugiert mit PE

Applikation: ELISA (Capture)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Klon: TX83

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu Allergin-1

Target: Allergin-1 (MILR1) (Mast Cell Immunoglobulin-Like Receptor 1 (MILR1))

Andere Bezeichnung: Allergin-1 (MILR1 Produkte)

Synonyme: Allergin-1 antikoerper, Gm885 antikoerper, Mca32 antikoerper, C17orf60 antikoerper, MCA-32 antikoerper, MCA32 antikoerper, mast cell immunoglobulin like receptor 1 antikoerper, mast cell immunoglobulin-like receptor 1 antikoerper, Milr1 antikoerper, MILR1 antikoerper

Hintergrund: Allergin-1, also known as mast cell Ag-32, is a 60 kD single pass transmembrane protein. It contains one Ig-like C2-type (immunoglobulin-like) domain in the extracellular region and one immunoreceptor tyrosine-based inhibitory motif (ITIM)-like domain in the cytoplasmic region. Allergin-1 is expressed on mast cells, dendritic cells, and macrophages as well as at low levels on neutrophils. After tyrosine phosphorylation, allergin-1 recruits PTPN6, PTPN11, and INPP5D, which results in a diminution of IgE-mediated degranulation in mast cells. No ligands have been identified for this molecule.