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- Target Alle CD43 (SPN) Antikörper anzeigen
- CD43 (SPN) (Sialophorin (SPN))
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD43 Antikörper ist konjugiert mit FITC
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Applikation
- Flow Cytometry (FACS)
- Aufreinigung
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
- Klon
- S11
- Isotyp
- IgG2b
- Top Product
- Discover our top product SPN Primärantikörper
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anti-Sialophorin (SPN) antibody
SPN Reaktivität: Human FACS, WB, IHC (p), IP Wirt: Maus Monoclonal MEM-59 unconjugated
anti-Sialophorin (SPN) antibodySPN Reaktivität: Human FACS, WB, IHC (p), IP, Func Wirt: Maus Monoclonal MEM-59 unconjugated
anti-Sialophorin (SPN) antibodySPN Reaktivität: Human FACS, WB, IHC, IF, StM Wirt: Maus Monoclonal DF-T1 unconjugated
anti-Sialophorin (SPN) (AA 276-400) antibodySPN Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Sialophorin (SPN) antibodySPN Reaktivität: Human FACS, WB, IHC, IF, StM Wirt: Maus Monoclonal rSPN-839 unconjugated Recombinant Antibody
anti-Sialophorin (SPN) antibodySPN Reaktivität: Human FACS, WB, IHC, IF, StM Wirt: Kaninchen Monoclonal SPN-1766R unconjugated Recombinant Antibody
anti-Sialophorin (SPN) antibody (FITC)SPN Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-59 FITC
anti-Sialophorin (SPN) antibody (Biotin)SPN Reaktivität: Human FACS, WB, IHC (p), IP Wirt: Maus Monoclonal MEM-59 Biotin
anti-Sialophorin (SPN) antibody (PE)SPN Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-59 PE
anti-Sialophorin (SPN) antibodySPN Reaktivität: Human, Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from prolonged exposure to light. Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- CD43 (SPN) (Sialophorin (SPN))
- Andere Bezeichnung
- CD43 (SPN Produkte)
- Hintergrund
- CD43, also known as Leukosialin and Ly48, is a 125 kD sialoprotein (glycosylated protein) expressed from 1.2 kBase mRNA in bone marrow-derived cells. This occurs early in development. Cells expressing CD43 include γ/δ T cells, macrophages, mature B cells, and dendritic cells. CD43 functions as an anti-adhesive surface molecule, promoted by antibody cross-linking, that releases the trailing edge of the cell during locomotion to allow movement of the cell body towards the lamellipodia. The intracellular distribution of CD43 is determined by binding to moesin, an intracellular membrane protein, which is in-turn bound in some manner to the actin cytoskeleton. Defects with CD43 function and expression retard cellular locomotion, resulting in a wide range of immune disorders. Wiscott-Alderich syndrome, and the varying degrees of its severity, is related to the dysregulation of CD43 expression.
- Pathways
- Regulation of Leukocyte Mediated Immunity
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