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2B4 Antikörper (FITC)
CD244
Reaktivität: Human
FACS
Wirt: Maus
Monoclonal
C1-7
FITC
Produktnummer ABIN2661609
Produktdetails anti-2B4 Antikörper (FITC)
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Target
Alle 2B4 (CD244) Antikörper anzeigen
2B4 (CD244)
(Natural Killer Cell Receptor 2B4 (CD244))
Reaktivität
Alle Reaktivitäten für 2B4 Antikörper
Human
Wirt
Alle Wirte für 2B4 Antikörper
Maus
Klonalität
Alle Klonalitäten für 2B4 Antikörper
Monoklonal
Konjugat
Alle Konjugate für 2B4 Antikörper
Dieser 2B4 Antikörper ist konjugiert mit FITC
Applikation
Alle Applikationen für 2B4 Antikörper
Flow Cytometry (FACS)
Aufreinigung
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Klon
C1-7
Isotyp
IgG1 kappa
Top Product
Discover our top product CD244 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Protect from prolonged exposure to light. Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu 2B4
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Target
2B4 (CD244)
(Natural Killer Cell Receptor 2B4 (CD244))
Andere Bezeichnung
CD244 (CD244 Produkte )
Synonyme
CD244 antikoerper, 2B4 antikoerper, NAIL antikoerper, NKR2B4 antikoerper, Nmrk antikoerper, SLAMF4 antikoerper, C9.1 antikoerper, F730046O15Rik antikoerper, Ly90 antikoerper, CD244 molecule antikoerper, CD244 natural killer cell receptor 2B4 antikoerper, CD244 antikoerper, Cd244 antikoerper
Hintergrund
CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including majority of CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.
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