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CCR7 Antikörper (FITC)

CCR7 Reaktivität: Human FACS Wirt: Maus Monoclonal G043H7 FITC
Produktnummer ABIN2661556
  • Target Alle CCR7 Antikörper anzeigen
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    Reaktivität
    • 113
    • 59
    • 36
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 74
    • 36
    • 21
    • 5
    Maus
    Klonalität
    • 68
    • 67
    • 1
    Monoklonal
    Konjugat
    • 57
    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCR7 Antikörper ist konjugiert mit FITC
    Applikation
    • 70
    • 58
    • 28
    • 23
    • 19
    • 16
    • 16
    • 15
    • 14
    • 9
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Kreuzreaktivität
    Cynomolgus, Rhesusaffen, Pavian
    Aufreinigung
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    Klon
    G043H7
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product CCR7 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from prolonged exposure to light. Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    Andere Bezeichnung
    CD197 (CCR7 Produkte)
    Hintergrund
    CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naive T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells, this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis.
    Pathways
    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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