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CD77 Antikörper (FITC)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD77 in FACS, IHC und IP. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN2661420

Kurzübersicht für CD77 Antikörper (FITC) (ABIN2661420)

Target

CD77

Reaktivität

Human

Wirt

  • 4
  • 1
  • 1
Maus

Klonalität

  • 5
  • 1
Monoklonal

Konjugat

  • 4
  • 1
  • 1
Dieser CD77 Antikörper ist konjugiert mit FITC

Applikation

  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Klon

5B5
  • Aufreinigung

    The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC and unconjugated antibody.

    Isotyp

    IgM kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Protect from prolonged exposure to light. Do not freeze.

    Lagerung

    4 °C

    Informationen zur Lagerung

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    CD77

    Hintergrund

    CD77, also known as Gb3S, A14GALT, A4GALT1, is a type II membrane protein. It was found specifically expressed on Burkitt's lymphoma cells and on a subset of germinal center B lymphocytes. CD77 has been described as a receptor for Shiga Toxin and Verotoxin 1 (VT1), which is produced by Shigella dysenteriae and some strains of E. coli . It is used as a marker for germinal center stage B-cells. CD19 has been reported as a ligand for D77 and their interaction functions in adhesion and signal transduction at a specific stage of B cell development. Studies have shown that cross-linking CD77 induces apoptosis in some B cell lines.
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