Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CD41, CD61 Antikörper (FITC)

Der Maus Monoklonal Anti-CD41, CD61-Antikörper wurde für FACS validiert. Er ist geeignet, CD41, CD61 in Proben von Human zu detektieren.
Produktnummer ABIN2661406

Kurzübersicht für CD41, CD61 Antikörper (FITC) (ABIN2661406)

Target

Alle CD41, CD61 Antikörper anzeigen
CD41, CD61 (CD41,CD61)

Reaktivität

  • 18
  • 7
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Human

Wirt

  • 28
Maus

Klonalität

  • 28
Monoklonal

Konjugat

  • 13
  • 5
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD41, CD61 Antikörper ist konjugiert mit FITC

Applikation

  • 24
  • 10
  • 6
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Flow Cytometry (FACS)

Klon

PAC-1
  • Aufreinigung

    The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC and unconjugated antibody.

    Isotyp

    IgM kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Protect from prolonged exposure to light. Do not freeze.

    Lagerung

    4 °C

    Informationen zur Lagerung

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    CD41, CD61 (CD41,CD61)

    Andere Bezeichnung

    CD41/CD61

    Hintergrund

    The gpIIb/IIIa complex, also known as integrin αIIbβ3, is expressed by megakaryocytes and platelets. It undergoes conformational changes upon activation by substances, such as ADP, thrombin, and TXA2, which subsequently reveals a ligand binding site that is specific for fibrinogen, von Willebrand factor (vWF), fibronectin, and vitronectin. This conformational change is crucial for platelet-platelet adhesion. Ligand bound gpIIb/IIIa complex promotes platelet aggregation. This complex plays an important role in hemostasis and is a target for developing therapeutic antibodies in immune thrombocytopenia.
Sie sind hier:
Chat with us!