Interleukin 17a Antikörper (Biotin)
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- Target Alle Interleukin 17a (IL17A) Antikörper anzeigen
- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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Reaktivität
- Human
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser Interleukin 17a Antikörper ist konjugiert mit Biotin
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Applikation
- Flow Cytometry (FACS)
- Kreuzreaktivität (Details)
- In sandwich ELISA, cross-reactivity with human IL-17F is negligible and no cross-reactivity with mouse IL-17A is present.
- Aufreinigung
- The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
- Klon
- Poly5189
- Isotyp
- IgG
- Top Product
- Discover our top product IL17A Primärantikörper
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anti-Interleukin 17A (IL17A) (AA 1-75) antibody
IL17A Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 4K5F6 unconjugated
anti-Interleukin 17A (IL17A) (Internal Region) antibodyIL17A Reaktivität: Human, Maus, Ratte ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 17A (IL17A) antibodyIL17A Reaktivität: Human ELISA, WB, Neut Wirt: Ziege Polyclonal unconjugated
anti-Interleukin 17A (IL17A) antibodyIL17A Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 17A (IL17A) antibodyIL17A Reaktivität: Human ELISA, FACS, ICC, IP Wirt: Maus Monoclonal 9F9 unconjugated
anti-Interleukin 17A (IL17A) antibody (FITC)IL17A Reaktivität: Human FACS Wirt: Maus Monoclonal 9F9 FITC
anti-Interleukin 17A (IL17A) antibody (APC)IL17A Reaktivität: Human FACS Wirt: Maus Monoclonal 9F9 APC
anti-Interleukin 17A (IL17A) antibody (PE)IL17A Reaktivität: Human FACS Wirt: Maus Monoclonal 9F9 PE
anti-Interleukin 17A (IL17A) (AA 24-133) antibodyIL17A Reaktivität: Human ELISA, WB Wirt: Maus Monoclonal 3G5 unconjugated
anti-Interleukin 17A (IL17A) (AA 24-155) antibodyIL17A Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.2 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 1 % BSA and 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
- Andere Bezeichnung
- IL-17A (IL17A Produkte)
- Hintergrund
- IL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts, the enhancement of surface expression of ICAM-1 in fibroblasts, activation of NF-κB and costimulation of T cell proliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells) mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63 % , 63 %, and 72 % amino acid sequence identity to rat IL-17A, mouse IL-17A, and a protein encoded by the ORF13 gene of herpesvirus Saimiri (HVS), respectively.
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