Kurzübersicht für TCR V Alpha7.2 Antikörper (APC-Cy7) (ABIN2660625)
Target
TCR V Alpha7.2
Reaktivität
Human
Wirt
Maus
Klonalität
Monoklonal
Konjugat
APC-Cy7
Applikation
Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
Klon
3C10
Produktmerkmale
The 3C10 antibody recognizes the Vα7.2 T cell antigen receptor (TCR) α -chain segment which, joined with the Jα33 segment, constitutes an invariant TCR that is characteristics of the mucosal-associated invariant T cells (MAIT cells). MAIT cells are restricted by a nonpolymorphic class Ib major histocompatibility complex (MHC) molecule, MHC-related molecule 1 (MR1). MAIT cells are present in human blood (1-8 % of T cells), mesenteric lymph nodes, liver, and intestinal mucosa. MAIT cells play a role in detecting and fighting off microbial infections.
Aufreinigung
The antibody was purified by affinity chromatography and conjugated with APC/Cy7 under optimal conditions. The solution is free of unconjugated APC/Cy7 and unconjugated antibody.