CD8 alpha Antikörper (PerCP-Cy5.5)
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- Target Alle CD8 alpha (CD8A) Antikörper anzeigen
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD8 alpha Antikörper ist konjugiert mit PerCP-Cy5.5
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Applikation
- Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)
- Kreuzreaktivität
- Schimpanse, Pavian, Cynomolgus, Rhesusaffen, Pigtailed Macaque, Sooty mangabey (Cercocebus atys)
- Aufreinigung
- The antibody was purified by affinity chromatography, and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCPE/Cy5.5 and unconjugated antibody.
- Klon
- RPA-T8
- Isotyp
- IgG1 kappa
- Top Product
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anti-CD8a Molecule (CD8A) (AA 22-235) antibody
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anti-CD8a Molecule (CD8A) antibodyCD8A Reaktivität: Maus FACS, IP, IHC (fro), IHC (p), ICC Wirt: Ratte Monoclonal 53-6-7 unconjugated
anti-CD8a Molecule (CD8A) antibody (FITC)CD8A Reaktivität: Maus FACS Wirt: Ratte Monoclonal 53-6-7 FITC
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anti-CD8a Molecule (CD8A) antibodyCD8A Reaktivität: Human IHC, StM, ISt Wirt: Maus Monoclonal C8-468 unconjugated
anti-CD8a Molecule (CD8A) (AA 28-196) antibodyCD8A Reaktivität: Maus, Ratte FACS, IHC, WB, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from prolonged exposure to light. Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- Andere Bezeichnung
- CD8a (CD8A Produkte)
- Hintergrund
- CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation, and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
- Pathways
- T-Zell Rezeptor Signalweg
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