Der PerCP-Cy5.5-konjugierte Ratte Monoklonal anti-CX3CR1 Antikörper (Klon 2A9-1) (ABIN2660175) detektiert spezifisch CX3CR1 in FACS und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
CX3CR1 is a G-protein-coupled seven-transmembrane chemokine receptor, also called GPR13 or V28. It is expressed on NK cells, T cell subset, monocytes/macrophages, dendritic cells, and some malignant epithelial cells. CX3CL1 (known also as fractalkine and neurotactin) is the ligand of CX3CR1. CX3CL1 is a unique transmembrane molecule with a CX3C-motif chemokine domain and a mucin-like stalk. CX3CL1 is expressed by activated-endothelial cells, neurons, and astrocytes. The interaction of CX3CR1 and its ligand mediates firm cell adhesion and migration.