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Neuropilin 1 Antikörper (PerCP-Cy5.5)

NRP1 Reaktivität: Maus FACS Wirt: Ratte Monoclonal 3E12 PerCP-Cy5.5
Produktnummer ABIN2660079
  • Target Alle Neuropilin 1 (NRP1) Antikörper anzeigen
    Neuropilin 1 (NRP1)
    Reaktivität
    • 103
    • 57
    • 51
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 93
    • 33
    • 5
    • 4
    Ratte
    Klonalität
    • 89
    • 46
    Monoklonal
    Konjugat
    • 55
    • 18
    • 15
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Neuropilin 1 Antikörper ist konjugiert mit PerCP-Cy5.5
    Applikation
    • 90
    • 33
    • 29
    • 29
    • 15
    • 14
    • 14
    • 11
    • 8
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
    Klon
    3E12
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product NRP1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from prolonged exposure to light. Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    Neuropilin 1 (NRP1)
    Andere Bezeichnung
    CD304 (NRP1 Produkte)
    Hintergrund
    CD304, also known as neuropilin-1, is a 140 kD type I transmembrane protein. Its extracellular region contains two CUB, two FV/FVIII, and one MAM domain. It is expressed by natural regulatory T cells (nTreg), a subset of invariant natural killer T cells (iNKT), endothelial cells, and neurons. Neuropilin-1 stabilizes the interaction between Tregs and dendritic cells, contributes to the recruitment of tumor-infiltrating Tregs in response to tumor-derived VEGF, and influences the process of angiogenesis and axon guidance. The ligands of CD304 are VEGF165 and semaphorin-3A.
    Pathways
    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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