ESAM Antikörper (APC)

Produktnummer ABIN2658754

Produktdetails anti-ESAM Antikörper (APC)

Target: ESAM (Endothelial Cell Adhesion Molecule (ESAM))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser ESAM Antikörper ist konjugiert mit APC

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Klon: 1G8-ESAM

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu ESAM

Target: ESAM (Endothelial Cell Adhesion Molecule (ESAM))

Andere Bezeichnung: ESAM (ESAM Produkte)

Synonyme: ESAM antikoerper, sc:d0254 antikoerper, W117m antikoerper, 2310008D05Rik antikoerper, Esam1 antikoerper, endothelial cell adhesion molecule antikoerper, endothelial cell adhesion molecule a antikoerper, endothelial cell-specific adhesion molecule antikoerper, ESAM antikoerper, esama antikoerper, Esam antikoerper

Hintergrund: Endothelial cell-selective adhesion molecule (ESAM) is a 55-kD membrane protein composed of two extracellular Ig domains, a single transmembrane domain, and a cytoplasmic domain. ESAM is predominantly expressed at endothelial junctions and on platelets, participating in the migration of neutrophils through the vessel wall by influencing endothelial cell contacts. It impacts vascular permeability and extravasation process. Recently, it was reported that ESAM is a novel marker for murine hematopoietic stem cells (HSCs) in fetal liver. ESAM expression is correlated with HSC activity. The ESAMHi population was highly enriched for multipotent myeloid-erythroid progenitors and primitive progenitors with lymphpoietic activity, and exclusively reconstituted long-term lymphohematopoiesis in lethally irradiated recipients.