L-Selectin Antikörper (APC)
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- Target Alle L-Selectin (SELL) Antikörper anzeigen
- L-Selectin (SELL) (Selectin L (SELL))
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Reaktivität
- Chemical
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser L-Selectin Antikörper ist konjugiert mit APC
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Applikation
- Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
- Kreuzreaktivität
- Schimpanse, Rind (Kuh)
- Aufreinigung
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
- Klon
- DREG-56
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product SELL Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from prolonged exposure to light. Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- L-Selectin (SELL) (Selectin L (SELL))
- Andere Bezeichnung
- CD62L (SELL Produkte)
- Substanzklasse
- Chemical
- Hintergrund
- CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naive lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.
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