Der APC-konjugierte Armenischer Hamster Monoklonal anti-GP5 Antikörper (Klon 1C2) (ABIN2658230) detektiert spezifisch GP5 in ICFC.
Dieser Antikörper reagiert spezifisch mit Proben aus Maus und Ratte.
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Protect from prolonged exposure to light. Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Target
GP5
(Glycoprotein V (Platelet) (GP5))
Andere Bezeichnung
CD42d
Hintergrund
CD42d is an 83 kD surface glycoprotein that non-covalently associates with GPIb and GPIX to form a receptor complex for von Willebrand factor on megakaryocytes and resting platelets. Binding sites for von Willebrand factor and thrombin have been localized to the GPIba chain of the GPI-b-V-IX complex. Platelet activation with thrombin cleaves the GPI-b-V-IX complex to release a 69 kD soluble fragment. Presence of the GPI-b-V-IX complex is important in Bernard-Soulier syndrome, a rare bleeding disorder.