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Neuropilin 1 Antikörper (APC)

NRP1 Reaktivität: Maus FACS Wirt: Ratte Monoclonal 3E12 APC
Produktnummer ABIN2658180
  • Target Alle Neuropilin 1 (NRP1) Antikörper anzeigen
    Neuropilin 1 (NRP1)
    Reaktivität
    • 112
    • 59
    • 52
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 103
    • 33
    • 5
    • 4
    Ratte
    Klonalität
    • 98
    • 47
    Monoklonal
    Konjugat
    • 58
    • 21
    • 16
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Neuropilin 1 Antikörper ist konjugiert mit APC
    Applikation
    • 101
    • 44
    • 39
    • 33
    • 16
    • 15
    • 14
    • 11
    • 10
    • 8
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    Klon
    3E12
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product NRP1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from prolonged exposure to light. Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    Neuropilin 1 (NRP1)
    Andere Bezeichnung
    CD304 (NRP1 Produkte)
    Synonyme
    NRP1 antikoerper, cd304 antikoerper, neuropilin antikoerper, np-1 antikoerper, npn-1 antikoerper, nrp antikoerper, nrp-1 antikoerper, vegf165r antikoerper, BDCA4 antikoerper, CD304 antikoerper, NP1 antikoerper, NRP antikoerper, VEGF165R antikoerper, C530029I03 antikoerper, NP-1 antikoerper, NPN-1 antikoerper, Npn1 antikoerper, Nrp antikoerper, neuropilin 1 antikoerper, neuropilin 1 L homeolog antikoerper, NRP1 antikoerper, nrp1 antikoerper, Nrp1 antikoerper, nrp1.L antikoerper
    Hintergrund
    CD304, also known as neuropilin-1, is a 140 kD type I transmembrane protein. Its extracellular region contains two CUB, two FV/FVIII, and one MAM domain. It is expressed by natural regulatory T cells (nTreg), a subset of invariant natural killer T cells (iNKT), endothelial cells, and neurons. Neuropilin-1 stabilizes the interaction between Tregs and dendritic cells, contributes to the recruitment of tumor-infiltrating Tregs in response to tumor-derived VEGF, and influences the process of angiogenesis and axon guidance. The ligands of CD304 are VEGF165 and semaphorin-3A.
    Pathways
    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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