CD1c Antikörper (Alexa Fluor 647)

Produktnummer ABIN2657681

Der Alexa Fluor 647-konjugierte Maus Monoklonal anti-CD1c Antikörper (Klon L161) (ABIN2657681) detektiert spezifisch CD1c in FACS und CyTOF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CD1c Antikörper (Alexa Fluor 647) (ABIN2657681)

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD1c Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Flow Cytometry (FACS), Mass Cytometry (CyTOF)

Klon: L161

Produktdetails anti-CD1c Antikörper (Alexa Fluor 647)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C

Details zu CD1c

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Andere Bezeichnung: CD1c

Hintergrund: CD1c, also known as R7 or M241, is a 43 kD member of the five CD1 antigens (CD1a-e) in humans. The CD1 Molecules are type I glycoprotein with structural similarities to MHC class I and are non-covalently associated with β2 -microglobulin, belonging to the Ig superfamily. CD1c is expressed on cortical thymocytes, Langerhans cells, dendritic cells, and a subset of B cells. It has been reported that CD1c is also expressed on mature T cells in a tightly regulated manner. CD1c is involved in antigen-presentation of glycolipids. It may also act in T cells as an immune regulatory molecule.