Panendothelial Cell Antigen Antikörper (Alexa Fluor 488)

Produktnummer ABIN2657569

Der Ratte Monoklonal anti-Panendothelial Cell Antigen Antikörper wird verwendet zum Nachweis von Panendothelial Cell Antigen in Proben von Maus. Er wurde validiert für FACS, IF und WB.

Kurzübersicht für Panendothelial Cell Antigen Antikörper (Alexa Fluor 488) (ABIN2657569)

Target: Panendothelial Cell Antigen

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Alexa Fluor 488

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)

Klon: MECA-32

Produktdetails

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C

Antigendetails

Target: Panendothelial Cell Antigen

Hintergrund: MECA-32 is a 50-55 kD homodimer glycoprotein primarily expressed on most endothelial cells in the embryonic and the adult mouse tissues, except in the brain and in skeletal and cardiac muscle, where it has more restricted distribution. In skeletal and cardiac muscle, the MECA-32 antigen is confined in small arterioles and venules. But in some conditions, such as inflammation or cardiac transplantation, MECA-32 expression can be induced on some negative-cardiac endothelial cells. In the brain, its expression occurs only in the circumventricular organs and the neurohemal tissues. During embryonic development, MECA-32 antigen is expressed on the brain vasculature up to day 16 of gestation, and disappears at day 17 and after.