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CD8 alpha Antikörper (Alexa Fluor 488)

Name: CD8 alpha Antikörper (Alexa Fluor 488)
SKU: ABIN2657486
Price: 361.83 EUR
Availability: InStock

CD8A Reaktivität: Human FACS, IHC Wirt: Maus Monoclonal HIT8a Alexa Fluor 488

FACS

1 image

Produktnummer ABIN2657486

Datenblatt (PDF)

Target Alle CD8 alpha (CD8A) Antikörper anzeigen

CD8 alpha (CD8A) (CD8a Molecule (CD8A))
Reaktivität
199

124

51

46

13

7

4

2

2

1

1

1

1

1

1

1

1
Human
Wirt
176

124

108
Maus
Passende Sekundärantikörper
Klonalität
306

97

2
Monoklonal
Konjugat
134

44

30

28

28

9

9

8

8

8

7

7

5

5

5

5

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD8 alpha Antikörper ist konjugiert mit Alexa Fluor 488
Applikation
317

118

91

69

64

52

34

21

15

14

14

12

11

9

7

7

6

6

5

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC)

Kreuzreaktivität

Schimpanse, Marmoset

Aufreinigung

The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Klon

HIT8a

Isotyp

IgG1 kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Protect from prolonged exposure to light. Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

The antibody solution should be stored undiluted between 2°C and 8°C
Target

CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Andere Bezeichnung

CD8a (CD8A Produkte)

Hintergrund

CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

Pathways

T-Zell Rezeptor Signalweg