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Integrin beta 3 Antikörper (Alexa Fluor 488)

Name: Integrin beta 3 Antikörper (Alexa Fluor 488)
SKU: ABIN2657462
Price: 155.29 EUR
Availability: InStock

ITGB3 Reaktivität: Maus, Ratte FACS Wirt: Hamster Monoclonal 2C9-G2 (HMbeta3-1) Alexa Fluor 488

FACS

1 image

Produktnummer ABIN2657462

Datenblatt (PDF)

Target Alle Integrin beta 3 (ITGB3) Antikörper anzeigen

Integrin beta 3 (ITGB3)
Reaktivität
184

98

67

17

15

13

12

9

8

8

5

2

2

2

1

1

1

1

1

1

1
Maus, Ratte
Wirt
120

68

15

2

2
Hamster
Klonalität
115

90
Monoklonal
Konjugat
108

16

12

11

8

4

4

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Dieser Integrin beta 3 Antikörper ist konjugiert mit Alexa Fluor 488
Applikation
125

94

54

46

32

30

24

20

15

13

13

5

5

5

3

3

3

2

2

1

1

1

1
Flow Cytometry (FACS)

Aufreinigung

The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Klon

2C9-G2 (HMbeta3-1)

Isotyp

IgG

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.5 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Protect from prolonged exposure to light. Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

The antibody solution should be stored undiluted between 2°C and 8°C
Target

Integrin beta 3 (ITGB3)

Andere Bezeichnung

CD61 (ITGB3 Produkte)

Hintergrund

CD61 is a 110 kD integrin β chain also known as β3 integrin or gpIIIa. It associates with the integrin αv chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate with the integrin αIIb chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets, megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts, and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelial adhesion is mediated by the binding of αv/β3 integrin or vitronectin receptor to CD31 (PECAM-1).

Pathways

Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex