ITGA5 Antikörper (Alexa Fluor 488)

Produktnummer ABIN2657450

Dieses Anti-ITGA5-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von ITGA5 in FACS und IHC. Geeignet für Maus.

Kurzübersicht für ITGA5 Antikörper (Alexa Fluor 488) (ABIN2657450)

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser ITGA5 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Klon: 5H10-27(MFR5)

Produktdetails anti-ITGA5 Antikörper (Alexa Fluor 488)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C

Details zu ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Andere Bezeichnung: CD49e

Hintergrund: CD49e is a 135 kD protein, also known as α5 integrin or VLA-5 α chain. It is a member of the integrin family, expressed on thymocytes, splenic B cells, activated T cells, and mast cells. CD49e associates with CD29 (integrin β1 chain) to form the fibronectin receptor (VLA-5). CD49e plays a critical role in both adhesion and T cell costimulation. The primary ligand for CD49e/CD29 (VLA-5) is fibronectin. The 5H10-27(MFR5) antibody has been shown to block CD49e mediated interactions and promote the in vitro stimulation of CD8+ T cells.

Pathways: Integrin Complex