Cytokeratin 19 Antikörper (Alexa Fluor 647)
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- Target Alle Cytokeratin 19 (KRT19) Antikörper anzeigen
- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Cytokeratin 19 Antikörper ist konjugiert mit Alexa Fluor 647
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Applikation
- Flow Cytometry (FACS), Blocking Reagent (BR), Functional Studies (Func)
- Aufreinigung
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
- Klon
- A53-B-A2
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product KRT19 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from prolonged exposure to light. Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C
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- Target
- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
- Andere Bezeichnung
- Cytokeratin 19 (KRT19 Produkte)
- Hintergrund
- Cytokeratin 19, also known as keratin 19, is a type I intermediate filament protein with a molecular weight of approximately 40-44 kD. Cytokeratin 19 is a heterotetramer composed of two type I and two type II keratin subunits. Unlike other cytokeratins, cytokeratin 19 lacks a C-terminal non-helical extension. This cytokeratin is widely expressed in the periderm (transient superficial layer enveloping developing epidermis), muscle, intestine, bile duct, esophagus, stomach, and thymus. Cytokeratin 19 can be upregulated by vitamin A and is thought to play a critical role in embryogenesis. Cytokeratin 19 intereacts with the pinin protein and has been shown to be modified by phosphorylation (Ser10, Ser35).
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