Der APC-konjugierte Ratte Monoklonal anti-CXCR4 Antikörper (Klon L276F12) (ABIN2656979) detektiert spezifisch CXCR4 in FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Maus.
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
CD184, also known as CXCR4, is a member of the G protein coupled receptor family that binds CXCL12 (SDF1). CXCR4 and CXCL12 play an important role in immune and inflammatory responses through the regulation of cell migration and growth. CXCR4 plays a crucial role in the pathogenesis of several autoimmune diseases such as atherosclerosis, rheumatoid arthritis, and wound healing. In addition, CXCR4 is the cofactor for fusion and entry of the T cell-tropic form of HIV-1.