Allergin-1 Antikörper (APC)

Produktnummer ABIN2656870

Der Maus Monoklonal anti-Allergin-1 Antikörper wird verwendet zum Nachweis von Allergin-1 in Proben von Maus. Er wurde validiert für FACS.

Kurzübersicht für Allergin-1 Antikörper (APC) (ABIN2656870)

Target: Allergin-1 (MILR1) (Mast Cell Immunoglobulin-Like Receptor 1 (MILR1))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Allergin-1 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: TX83

Produktdetails anti-Allergin-1 Antikörper (APC)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C

Details zu Allergin-1

Target: Allergin-1 (MILR1) (Mast Cell Immunoglobulin-Like Receptor 1 (MILR1))

Andere Bezeichnung: Allergin-1

Hintergrund: Allergin-1, also known as mast cell Ag-32, is a 60 kD single pass transmembrane protein. It contains one Ig-like C2-type (immunoglobulin-like) domain in the extracellular region and one immunoreceptor tyrosine-based inhibitory motif (ITIM)-like domain in the cytoplasmic region. Allergin-1 is expressed on mast cells, dendritic cells, and macrophages as well as at low levels on neutrophils. After tyrosine phosphorylation, allergin-1 recruits PTPN6, PTPN11, and INPP5D, which results in a diminution of IgE-mediated degranulation in mast cells. No ligands have been identified for this molecule.