DLL1 Antikörper

Produktnummer ABIN2656778

Produktdetails anti-DLL1 Antikörper

Target: DLL1 (delta-Like 1 (DLL1))

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser DLL1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktmerkmale: The Notch receptors and their ligands are highly conserved from invertebrates to mammals. The Delta-like 1 (DLL1) is one of the four or five Notch ligands identified. The binding to Notch receptor results in the proteolysis of Notch and movement of intracellular portion of Notch into the nucleus.This translocation triggers a series of signaling process. Delta-like 1 is reported to be essential for the maintenance of marginal zone B cells in normal mice, and engagement of Notch 1 by DLL1 promotes differentiation of B lymphocytes to antibody-secreting cells.

Aufreinigung: The antibody was purified by affinity chromatography.

Klon: HMD1-3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted between 2°C and 8°C. Do not freeze.

Details zu DLL1

Target: DLL1 (delta-Like 1 (DLL1))

Andere Bezeichnung: DLL1 (DLL1 Produkte)

Pathways: Notch Signalweg, Stem Cell Maintenance