Integrin beta 5 Antikörper

Produktnummer ABIN265481

Der Kaninchen Polyklonal Anti-Integrin beta 5-Antikörper wurde für WB und EIA validiert. Er ist geeignet, Integrin beta 5 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Integrin beta 5 Antikörper (ABIN265481)

Target: Integrin beta 5 (ITGB5)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Integrin beta 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Integrin beta 5 Antikörper

Spezifität: This antibody antibody detects endogenous levels of Integrin beta5 protein. (region surrounding Val746)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Integrin beta 5

Target: Integrin beta 5 (ITGB5)

Andere Bezeichnung: Integrin beta-5 / ITGB5

Hintergrund: Integrins are heterodimers composed of noncovalently associated transmembrane alpha and beta subunits. The 16alpha and 8beta subunits heterodimerize to produce more than 20 different receptors. Most Integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain Integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster Integrins by binding to adjacent Integrin receptors, both receptor clustering and ligand occupancy are necessary for the activation of Integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, Integrins function as signaling receptors. Signals transduced by Integrins play a role in many ,biological processes, including cell growth, differentiation, migration and apoptosis.Synonyms: ITGB-5

Molekulargewicht: approx. 88 kDa

Gen-ID: 3693

NCBI Accession: NP_002204

UniProt: P18084

Pathways: Integrin Complex