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CARD6 Antikörper

CARD6 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN265333
  • Target Alle CARD6 Antikörper anzeigen
    CARD6 (Caspase Recruitment Domain Family, Member 6 (CARD6))
    Reaktivität
    • 37
    • 2
    • 2
    Human
    Wirt
    • 34
    • 2
    • 1
    Kaninchen
    Klonalität
    • 35
    • 2
    Polyklonal
    Konjugat
    • 15
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CARD6 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 19
    • 13
    • 13
    • 8
    • 8
    • 7
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects endogenous levels of CARD6/CIN protein (region surrounding Ala2).
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Reinheit
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product CARD6 Primärantikörper
  • Applikationshinweise
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CARD6 (Caspase Recruitment Domain Family, Member 6 (CARD6))
    Andere Bezeichnung
    CARD6 (CARD6 Produkte)
    Synonyme
    D730008L15 antikoerper, CARD6 antikoerper, CINCIN1 antikoerper, caspase recruitment domain family, member 6 antikoerper, caspase recruitment domain family member 6 antikoerper, Card6 antikoerper, CARD6 antikoerper
    Hintergrund
    Membrane-associated guanylate kinase (MAGUK) family members localize to the plasma membrane and function as molecular scaffolds for the assembly of multi-protein complexes. The MAGUK family includes several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product, such as postsynaptic proteins, GKAPs, the tight junction associated proteins (ZO-1-3) and the caspase-associated recruitment domain (CARD) proteins, CARD 6, CARD 8-12 and CARD 14. CARD 6 is a 311 amino acid protein that associates with microtubules and acts as a selective mediator of NFκB activation. CARD 6 is structurally and functionally related to the superfamily of interferon (IFN)-inducible GTPases, a group that comprises host defense proteins which mediate cell-autonomous immunity. RICK, the receptorinteracting protein (RIP)-like interacting caspase-like apoptosis regulatory protein kinase, interacts with CARD 6 and targets it to aggresomes, regions of the cell where protein aggregates collect.Synonyms: Caspase recruitment domain-containing protein 6
    Molekulargewicht
    approx. 116 kDa
    Gen-ID
    84674
    NCBI Accession
    NP_115976
    UniProt
    Q9BX69
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